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The lyophilized powder has a distinctive blue color due to the d^9 electronic configuration of Cu(II) in the peptide complex

however, this theory has been called into question as APAP-protein adducts have been detected at 1 hour after APAP treatment, a time that that would precede GSH depletion

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To verify that FXR1 depletion promoted ferroptosis is dependent on GPX4, the expression of GPX4 was forced in cells lacking FXR1 (Figure 6O)

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Of these, 794 were excluded after abstracts screening and identified articles in languages other than English, lack of full text or being review articles, case reports, animal or in-vitro studies