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12 Animal studies overexpressing TRX such as the TRX transgenic mice (TRX-Tg) helped elucidate the role of TRX in suppressing inflammation
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After a one-month break, healthcare providers typically recommend restarting at a lower doseoften 2.5 mg weeklythen gradually re-escalating to minimize gastrointestinal side effects while restoring metabolic benefits
The most commonly reported side effects are nausea, upset stomach, and reduced appetite particularly when first starting the medication or when the dose increases
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