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Under the regulation of AMPK in the ventral medial hypothalamus, they could promote the conversion of visceral white adipose tissue (WAT) to brown adipose tissue (BAT), promoting thermogenesis of BAT and thus energy consumption (182)

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(Extended reading: After Tirzepatide's approval for the treatment of obesity, how long will it be before Eli Lilly's small molecule GLP-1R agonist becomes available?) Volenrelaxin (LY3540378) is a long-acting synthetic relaxin analogue that acts as an agonist for the relaxin family peptide receptor 1 (RXFP1), developed by Eli Lilly for the treatment of chronic heart failure

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