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Research is still ongoing to evaluate its long-term safety
This means your body has a harder time metabolizing blood sugar
10.1093/cvr/cvv208 101
Because it remains under study, its dosing, approved uses, and safety profile have not been established by an FDA-approved label
In contrast, the concordance of benchmarking results for all outcomes, including mortality, in the SURPASS-CVOT emulation study comparing tirzepatide to dulaglutide provided support for the validity of evaluating these outcomes in expanded study populations
Cardiovascular and Metabolic Benefits : Semaglutide, as demonstrated in the SELECT trial, has established long-term cardiovascular benefits, with an average weight loss of 10.2% over four years, highlighting its role in cardiometabolic risk reduction
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