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However, as this is an observational study, future long-term follow-up studies and randomized clinical trials are required to confirm its actual preventive efficacy and clinical applicability.", said Professor Jang Yun-hyeok(Specialization Center for National Strategic TechnologyDepartment of Neurology)

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151 Leptin-deficient mice (ob/ob) causes both obesity and diabetes due to hyperphagia and blunted metabolic rate, and treatment with exogenous leptin could prevent and reverse the obese phenotype