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It is involved in mitochondrial oxidative phosphorylation, indirectly regulates extra-mitochondrial metabolic pathways, and protects cells against excessive ROS generation (90)

doi:10.1056/NEJMoa2416394 Harbi M, Ashour A, Alorfi N, et al

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Its research profile makes it especially relevant for studies focused on metabolic flexibility, mitochondrial energy output, exercise-related signaling, cardiometabolic models, fatty acid utilization, and cellular energy demand

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To put this into perspective: Someone weighing 120 kg could potentially lose around 29 kg , although individual results vary considerably