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Terrana & Sandy

(Biochem Pharmacol 2018) documented a reduction of -35% in white adipose tissue, -40% in adipocyte volume, -5.1% in body weight and -30% in plasma cholesterol in just 11 days in obese mice (DIO), without any change in food intake

It can also obscure the fact that there is no validated human use, dose, safety profile or approved indication

They are not FDA-approved for weight loss

There is considerable literature about the oddities of the prescribing habits of British doctors , the factors influencing them, and the attitudes of doctors to prescription, but there have been as far as we know, no attempts to compare quantitatively the expected amount prescribed, on the basis of good clinical practice, with that actually prescribed