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It is an effective drug for the treatment of different cancer types, rheumatoid arthritis, psoriasis, Crohns disease and multiple sclerosis treatment 2
Best, S
Celik L, Ozturkcan O, InalL TC, Canacankatan N, Kayrin L
The mechanism is that GLP-1 exerts its glucagon inhibitory effect in human pancreatic islets through an intrinsic (non-paracrine) PKA-dependent effect mediated by the activation of the few GLP-1Rs present in the plasma membrane of -cells, which ultimately inhibits P/Q-type Ca2+ channels (Ramracheya et al., 2018)
Melanie Avalon So this is UK, right