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Disease improvement was assessed by the psoriasis area severity index (PASI), epidermal thickness, histological changes (skin-homing chemokines CCL17, Th17, Tc17, T22, CD3 +, CD4 +/CD8 +, CLA), and quality of life (dermatology life quality index)

A 2021 randomised, double-blind study showed, people who stopped using Ozempic after 20 weeks regained 7% body weight while those who continued the weekly injections lost a further 8% body weight

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GLP-1 receptor agonists like semaglutide and tirzepatide have transformed the treatment of type 2 diabetes and obesity

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