Granata A, Maccarrone R, Anzaldi M, Leonardi G, Pesce F, Amico F, et al
NAD+ therapy aims to restore intracellular energy pathways and support sirtuin activation linked to longevity
SURMOUNT-2 (N=938), conducted in patients with type 2 diabetes and obesity, showed 14.7% weight loss with tirzepatide 15 mg versus 3.2% with placebo, along with a 2.1 percentage point reduction in A1C [15]
When activated with GLP-1r, GIP seems to potentiate not only the weight loss mechanism of the incretin but also the glucose lowering effects [13]
Priya N Patel, Claudia K Fox, Megan O Bensignor, Eric M Bomberg, Weight Loss From Combination Anti-Obesity Medication Regimens Can Approach that Achieved From Bariatric Surgery, JCEM Case Reports, Volume 1, Issue 1, January 2023, luac038,
It is the most physically restorative sleep phase: during delta sleep, growth hormone secretion peaks (~70% of daily secretion), tissue repair processes are maximized, and immune cytokine production is elevated