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Sani M-A, Separovic F
What are GLP1s and why do they matter
The market is expanding at a CAGR of 17.49% between 2025 and 2034
Cardiovascular safety data from published trials showed reductions in systolic blood pressure (ranging from 4.3 to 7.9 mmHg depending on dose) and diastolic blood pressure (2.3 to 4.6 mmHg reductions)
This process is stimulated by enterocyte AMP kinase(AMPK), triggered by opening of Cav 1.3 Ca 2+ channels following SGLT1-dependent depolarization of the apical membrane potential 7
Standard doses work for many, but some need adjustments
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