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These cells produce intrinsic factor , a protein needed for Vitamin B12 absorption
This can impair nutrient absorption from food, contribute to symptoms and cause long-term health problems
BMJ Open 10 (8), e033687
This stage requires prompt treatment to prevent further complications
For individuals requiring supplementation due to confirmed deficiency or malabsorption, therapeutic doses vary considerably depending on the underlying cause: Dietary deficiency : 50150 micrograms daily orally, or cyanocobalamin tablets as prescribed Pernicious anaemia : Initially hydroxocobalamin 1 mg intramuscularly three times weekly for two weeks, then maintenance injections every two to three months [3] Neurological involvement : More intensive regimens may be required, with hydroxocobalamin injections on alternate days until symptom improvement [3] NICE guidance emphasises that supplementation should be evidence-based rather than speculative
A correctly mixed solution should be perfectly clear
