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The 2017 Neelakantan paper in Biochemistry characterised a fluorescent assay for direct real-time monitoring of NNMT enzymatic activity, providing the analytical foundation for inhibitor screening including 5-Amino-1MQ (PMID 28121423)
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Additionally, researchers have speculated that AHK-Cu might influence the transition and duration of hair growth phases, particularly the anagen stage, although further confirmation is needed
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doi:10.1074/jbc.R113.458810
Research from the STEP trial program shows that 1.0 mg is where the dose-response curve starts to steepen meaningfully
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