External resources STEP 1 Trial: Semaglutide in Adults with Overweight or Obesity (NEJM) SURMOUNT-1 Trial: Tirzepatide for Treatment of Obesity (NEJM) NIH BMI Calculator (National Heart, Lung, and Blood Institute) For researchers serious about navigating GLP-1 eligibility and optimizing their treatment protocols, SeekPeptides offers the most comprehensive resource available
In mice with DSS-induced colitis, treatment with 3.6 M Amuc_1409* per day induced body weight gain, increased colon length and lowered the histopathological score in the distal colon
MetabolismClinical and Experimental
The size for the obesity GLP-1 market is projected to reach USD 65,364 million by 2035
In humans, retrospective cohort studies have found people taking GLP-1RAs are less likely to develop alcohol use disorder (AUD) 16 and less likely to be hospitalized for acute alcohol intoxication 17
However, potential AEs were also highlighted, emphasizing the need for careful evaluation in clinical practice to ensure proper usage