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Why the Evidence Still Needs Restraint The authors rated most included studies as having some concerns or high risk of bias under the Cochrane RoB 2 tool, and GRADE certainty was low to very low across outcomes.Small samples, varied doses, varied routes of administration, and varied imaging tasks make it hard to know whether differences between studies reflect real biology or methodological noise
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Studies show it boosts growth hormone without spiking other hormones like cortisol or prolactin, which can lead to unwanted side effects
However, if you have trouble getting enough protein from foods, supplements are a viable option
Circulating inflammatory molecules Early ME/CFS has been associated with elevated proinflammatory cytokines (227230) and a distinct cytokine inflammatory profile (225, 231)
