is tirzepatide still on the shortage list off What Tirzepatide Used for? Approved and Potential Uses FDA says this weight loss

The major part of the flux is carried by the low affinity transporter, which has sigmoidal kinetics with a V max in the range 9001400 M/hr, a K m of approximately 3000 M, and a Hill coefficient of approximately 3 [3436]

While these findings are encouraging, further human trials are needed to confirm the effectiveness of this approach

Replete smartly

People with kidney disease should seek medical advice before increasing protein intake

Treatment may change or stop when the risks, side effects, or results no longer support continued use

This is not a failure of the medication but rather a reflection of how obesity works as a chronic condition