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Emerging evidence highlights a range of contributing factors, including reduced mechanical loading, increased bone marrow adiposity, hormonal and endocrine alterations, nutritional deficiencies, and disruptions in energy metabolism

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We classified prescriptions for Mounjaro and Ozempic (approved for T2DM) as on-label if the patient had a history of T2DM and off-label otherwise

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de Zoysa N, Rogers H, Stadler M, Gianfrancesco C, Beveridge S, Britneff E, et al