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The NIH sets a hard upper limit for vitamin D consumption at 4,000IU, or 100mcg.56 Calcium As with vitamin D, theres a risk of getting too much calcium from supplementation, with the NIHs upper limits set to 2,500mg for adults under 51 and 2,000mg for older adults.57 Collagen Collagen is generally very safe to consume, even in large doses

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During the treatment, no significant change in the body weight of the mice was observed, indicating that NP4 has a high biocompatibility (Supplementary Fig

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