R., Sherman, M
Theoretical risks Long-term or high-frequency use raises theoretical concerns about copper accumulation
The hydrodynamically relevant endothelial cell glycocalyx observed in vivo is absent in vitro
Conventional antioxidants are limited by poor mitochondrial specificity, but mitochondria-targeted compounds offer greater potential (Xiao et al., 2017)
Spherical nucleic acid nanoparticle conjugates as an RNAi-based therapy for glioblastoma
Furthermore, in spite of considerable research efforts (Dixon et al., We propose a model describing the diverse roles of plant GSTs in the interactions of plant hosts with pathogenic microbes considering four different plant-pathogen interaction types (Table 1): (1) symptomless resistance (including basal resistance to bacteria and symptomless R gene-mediated resistance to viruses), (2) HR-associated resistance, (3) limiting susceptibility to systemic spread of pathogens and plant cell/tissue death (during infections by hemibiotrophic/necrotrophic fungi, bacteria, and viruses), (4) promoting susceptibility to biotrophic fungi and viruses (maintaining reduced conditions in infected non-necrotic plant tissues)