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Kidney: In January 2025, the FDA approved semaglutide for reducing the risk of kidney failure and disease progression in patients with diabetes and chronic kidney disease the first GLP-1 agent indicated for CKD

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You deserve a clear answer to each

Sold under the trade names Ozempic, Wegovy and Rybelsus, the drug was initially developed for the treatment of Type 2 diabetes, helping to manage blood sugar levels

For instance, genes which are important for ferroptosis resistance [e.g., ACSL3 , ferritin heavy chain ( FTH1 ), GPX4 , GSS and voltage-dependent anion channel 2 and 3 ( VDAC2/3 )] are downregulated in an early stage of AD pathology but upregulated at later AD stage