[PMID: 5793155] PubMed record related to this compound for laboratory literature review
Alogliptin did not demonstrate any major toxicities in combination with pioglitazone or metformin as well [17] (Table 2)
Sources Review of GLP-1 Medicines for Obesity and Symptoms in Menopause Fat Mass Changes During Menopause: a Metaanalysis The 2023 Nonhormone Therapy Position Statement of The North American Menopause Society Vasomotor Symptoms Across the Menopause Transition: Differences Among Women The Impact of the Menopausal Transition on Body Composition and Abdominal Fat Redistribution Wilding JPH et al
Who Should Be Cautious Anyone who is pregnant or breastfeeding, unless a clinician specifically approves it
A randomized, parallel group, double-blind, multicentre study comparing the efficacy and safety of Avandamet (rosiglitazone/metformin) and metformin on long-term glycaemic control and bone mineral density after 80 weeks of treatment in drug-naive type 2 diabetes mellitus patients
Nausea Vomiting Diarrhea Constipation Decreased appetite Injection-site reactions Gallbladder events (cholelithiasis, cholecystitis) reported in some Phase 2 participants Increased heart rate Possible pancreatitis (per GLP-1 class data not specifically reported in retatrutide trials) Frequently asked questions Is retatrutide FDA-approved