Based on this, an investigator-initiated, phase III, double-blind, randomized controlled trial was performed to evaluate the efficacy and safety of high-dose selenium (2000 g/day) intravenously in a 1:1 ratio for the prevention of CIPN in 68 platinum-sensitive cancer patients treated with paclitaxel, carboplatin, and bevacizumab [110]
The injection typically takes about 15-30 minutes
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Ginsenoside Rh3 induces pyroptosis and ferroptosis through the Stat3/p53/NRF2 axis in colorectal cancer cells