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Nonetheless, it is also clear that intra-islet GLP-1R signaling is essential for GSIS, with more evidence that an intra-islet paracrine GLP-1 signaling is physiologically present (212, 213) and necessary for -cell health under metabolic (214)

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Individual traits and consumption methods also matter

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Anxiety can deepen the same loop, since excessive worry often brings muscle tension, restlessness, and trouble concentrating, symptoms detailed by the Mayo Clinic in its guide to generalized anxiety disorder

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This makes it valuable for managing these symptoms during chemotherapy, radiation, or after surgery, helping individuals maintain their daily activities and nutrition

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