It is the active form of glutathione, which exists in two statesreduced (GSH) and oxidized (GSSG)
doi:10.1007/s11095-015-1652-z
Accordingly, we found that in vitro activation and the costimulatory potential of GSH-deficient FoB was decreased compared to control cells upon 24h stimulation as indicated by lower expression of CD25, CD69, GL-7 and CD80/CD86 (Supplementary Fig
In this study, we show that nearly half of the human thyroid cancer specimens have increased GPX4 expression compared to control normal thyroid tissue and that the GPX4 overexpression is associated with worse overall survival
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