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Despite reports of positive outcomes from simultaneous agonism of both GLP-1R and Y2-R, this approach alone has not generated the same clinical benefits as obesity surgery 64,65,66
The same trials are also the only window onto long-term safety: what are the implications of the elevated resting heart-rate in patients with heart failure or irregular heartbeats, let alone healthy individuals considering the longer term health implications of these drugs
water content
By helping maintain cellular integrity and mitochondrial efficiency, it may also promote energy production and healthy aging
Any anti-inflammatory effects are considered secondary
Close monitoring during treatment is recommended, and medical help should be sought if symptoms like reduced urine output, swelling, or unusual weakness occur
