tirzepatide once weekly for the treatment of obesity journal club in people with type 2 diabetes (SURMOUNT-2): a double-blind, randomised, multicentre, placebo-controlled, phase 3 trial Tirzepatide (Zepbound) for the Treatment

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Glucagon-like peptide-1 (GLP-1) is a peptide hormone produced by enteroendocrine cells at low basal levels, but also by neurons in the caudal medulla [7]

Retrieved 20 February 2020

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Additional symptoms include poor balance, confusion, difficulty remembering, and depression

The 10-14 days on, 7+ days off pattern prevents tolerance development and maintains effectiveness over longer timeframes