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People who experience anxiety, agitation, headaches, or insomnia from methyl-B12 may benefit from switching to hydroxocobalamin under practitioner guidance

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2 Materials and Methods 2.1 Reagents Hexadecyltrimethylammonium bromide (CTAB) (99%), ethyl acetate (99.5%), ammonium hydroxide solution (28%), tetraethyl orthosilicate (TEOS) (98.5%), calcium nitrate tetrahydrate (99%), zinc nitrate hexahydrate (98.5%), absolute ethanol (99.9%) were used to synthesize the bioactive glass