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This phase is usually temporary, often resolving within 4-8 weeks as the skin completes its accelerated renewal cycle

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For data analysis, the raw data were processed with DIA-NN (v.1.9.2

Cullin-RING ligases (CRLs) are the largest family of E3 ubiquitin ligases, which have essential role in controlling numerous cancer-relevant proteins ubiquitylation and proteasomal degradation 1

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