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It was developed by Novo Nordisk and described by Raun et al
Their favorable bioactivity profile, combined with high tissue penetration and low immunogenicity, supports their integration into advanced delivery platforms such as hydrogels or topical formulations [14, 29]
Signs suggesting cycle extension include continued gradual improvement at cycle end, incomplete resolution of primary concerns, and recent flare or setback
Briefly, after enrichment, FoB were washed and resuspended in mannitol and sucrose-BSA (MAS-B) buffer pH 7.2 (70 mM sucrose, 220 mM Mannitol, 10 mM KH 2 PO 4 , 5 mM MgCl 2 , 2 mM Hepes, 1 mM EGTA, and 0.4% fatty acid-free BSA), and flux measurements were started
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