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We may speculate that a larger reduction of plasma aldosterone in the patients with advanced CKD seen in our study could be caused by a higher local activity of RAAS due to kidney dysfunction
Tuxhorn JA, McAlhany SJ, Dang TD, Ayala GE, Rowley DR
[1] [4] The reason researchers may compare them is simple: Tesamorelin acts through the GHRH receptor (GHRH-R), while Ipamorelin acts through the growth hormone secretagogue receptor (GHS-R1a) pathway
This approach also allows for indefinite treatment as long as the medication remains effective and well-tolerated
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