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Overdose Effects Overdose : Overdose of up to 4 mg in a single dose and up to 4 mg in a week have been reported in clinical trials

Half lost at least 15 percent of their starting weight, compared with 5.6 percent taking the placebo

Predrag Sikiric's research group at the University of Zagreb, Croatia, beginning in the early 1990s

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A critical consideration in interpreting metabolism studies is that substantial weight loss from any method typically results in decreased absolute energy expenditure