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Heparinized blood was used for automated blood gas analysis (GEM Premier 4000, Werfen, Kirchheim, Germany) immediately after sampling to determine oxyhemoglobin (oxy-HGB), deoxyhemoglobin (deoxy-HGB), carboxyhemoglobin (carboxy-HGB) and methemoglobin (met-HGB)
These enzymes bind toxins to glutathione molecules, making them water-soluble for easy elimination through bile or urine
For this purpose, air-dried blood smears were prepared and stained according to Pappenheim
Tumor initiation and early tumorigenesis: molecular mechanisms and interventional targets
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