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Phase 2 trial data (NEJM, 2023) showed substantial MRI-PDFF-measured liver fat reductions at 8 mg and 12 mg weekly doses, with some participants falling below the 5% hepatic steatosis threshold
The most commonly prescribed medication is phentermine
In a study comparing the two drugs for weight loss, people lost an average of 5.9% of their body weight in three months with tirzepatide, compared to 3.6% with semaglutide
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Although no cases have been reported in humans, some studies have reported a possible association between GLP-1 agonist use and increased risk of thyroid cancer
Do not double up your dose if you forget and five days have passed
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