Cilla DD Jr, Whitfield LR, Gibson DM, Sedman AJ, Posvar EL
It ranks fourth because the medication pricing variability makes it hard to budget, and the intake depth is lighter than the top three
In other words, the excitement is real, and so is the caution
For the primary composite outcome and secondary hierarchical outcomes, the threshold for two-sided statistical significance was set to 0.0322 (one-sided level 0.00161) using Lan-DeMets alpha spending function, which allows to adjust significance levels as data were reviewed for the interim analysis, reducing the chance of false positive results
Egecioglu et al., 2013b
Confirmed molecular weight near 9,200 Da (the exact theoretical value for the 83-amino-acid sequence)