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in 2.7% of those receiving placebo, resulting in a reduction of 39% in the hazard ratio in favor of the GLP1AR (HR = 0.61

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AST/Bex also upregulated the expression of ABCA1, LRP1, and/or APOA-I, thereby facilitating cholesterol efflux partially through PPAR/RXR activation, and downregulated cholesterol biosynthesis and esterification

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