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employed the GLUT1 transporter to facilitate the delivery of antisense oligonucleotides (ASOs) by designing GLUT1-targeted ASO-loaded glucosylated-polyion complex micelles (Glu-PIC/Ms) in mice models

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We also found that tamoxifen stimulated the accumulation of several ceramide species, increased PARP cleavage and JNK activation

The reduced model (Figure 2A) is crucial in that it contains all of the components that are relevant to the dynamics of the methionine cycle even when excised from the full network

Each monomer has a catalytic nicotinamide adenine dinucleotide phosphate (NADP + )-binding domain and + domain, containing an additional binding site for NADP + that structurally stabilizes the enzyme (Fig

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