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TMQ0153 treatment induced H2AX expression in MV4-11 cells, which was followed by a decrease, likely due to the onset of cell death (Fig

Analyses of TIF from tumours with WT Gclc and with Gclc knocked out (KO) showed that intracellular GSH synthesis partially contributed to tGSH levels in the TIF but not serum (Extended Data Fig

Am J Transl Res (2016) 8:475063

Luo M, Wang D, Delaplace P, Pan Y, Zhou Y, Tang W, et al

Controlled drug delivery with nanoassemblies of redox-responsive prodrug and polyprodrug amphiphiles

The - glutamyl amino acids or oxoproline could be signaling molecules to activate the transport of amino acids through membranes