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1987;253(2):E20813
Partial reversal was obtained by feeding acetyl-L-carnitine and/or R-alpha -lipoic acid [144]
Figure 9 3.8 Proposed substrate recognition and enzyme mechanism of MSA-DH The potential substrate binding site of MSA-DH was explored by superimposing the three-dimensional structure of human succinic semialdehyde dehydrogenase in complex with its substrate (PDB ID: 2W8Q) (Supplementary Figure S1)
For most people, including those with thyroid conditions (except MTC and MEN2), the benefits of treatment outweigh theoretical thyroid concerns that have not been confirmed in human studies
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