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Metastatic or primary lung tumours were shown to rely on enhanced expression of NFS1 to maintain the supply of FeS clusters as co-factors of multiple essential proteins and enzymes in the cell that are exposed to (damaging) high oxygen concentrations

[PMID: 2230538] PubMed record related to this compound for laboratory literature review

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Onodera Y, Motohashi H, Takagi K, Miki Y, Shibahara Y, Watanabe M, Ishida T, Hirakawa H, Sasano H, Yamamoto M, Suzuki T (2014) NRF2 immunolocalization in human breast cancer patients as a prognostic factor