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52-WEEK RESULTS Statistically significant weight reduction with RYBELSUS 14 mg and 7 mg vs Januvia 2,4* RYBELSUS is not indicated for weight loss

This is a normal tissue response and not cause for concern

A three-year study of tirzepatide a medication approved in the US as Mounjaro for diabetes and Zepbound for weight loss found that when adults who had prediabetes and obesity or overweight used it weekly, it lowered their risk of progression to diabetes by 94% compared with a placebo, according to drugmaker Eli Lilly

It is primarily studied for its role in regulating metabolism, glucose control, and appetite

In one study, researchers found that IGF-1 causes the proliferation of myofibroblast in a dose-dependent manner