Advancements in technology, such as connected pen caps t hat track medication use and integrate data with smartphone applications, will enhance patient engagement and adherence
In the landmark STEP 1 trial, published in the New England Journal of Medicine in 2021, patients taking semaglutide 2.4 mg (Wegovy) lost an average of 14.9% of their body weight over 68 weeks, compared to 2.4% in the placebo group
Alli is the brand-name version that can be found over-the-counter (OTC) and is not usually covered by insurance
Gastrointestinal side effects that are manageable alone can become intolerable together
Table 1 Possible association between glucagon-like peptide 1 (GLP-1) and depression based on previous studies
In the matched non-nave cohorts, 21% of tirzepatide ( N = 1173) and 20% of semaglutide ( N = 1130) patients had follow-up HbA1c data