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Collagen also exhibits an affinity for water, and it appears to hydrate the skin cells and Extracellular Matrix when it penetrates the skin barrier

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PMID: 19180561

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References Ferrari G, Cook BD, Terushkin V, Pintucci G, Mignatti P

Further experimentation involved Annexin V-fluorescein isothiocyanate/propidium iodide labeling and flow cytometric analysis, which suggested that AHK-Cu may have reduced the number of apoptotic DPCs, although this decrease was not statistically significant and thus not conclusively confirmed