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The lyophilization process creates slightly different textures each time
Because a single ferroptosis pathway is more likely to trigger resistance to ferroptosis, multiple pathways should be coupled to promote ferroptosis in tumor cells at the same time
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TMAO can change the bile acid spectrum to accelerate the formation of aortic lesions in ApoE / mice, and further activate the nuclear receptors farnesoid-X-receptor (FXR) and small heterodimer partner (SHP), to reduce the expression of cholesterol 7-hydroxylase (Cyp7a1) to inhibit bile acid synthesis, thus accelerating the formation of atherosclerosis (82)
