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GLP-1RAs promote weight loss by suppressing appetite and delaying gastric emptying, whereas SGLT2is reduce weight by decreasing body water through osmotic diuresis and increasing urinary calorie excretion 33

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Amelia Cobo: conception and design of the work

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Diabetologia (2017) 60(9):180112

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This study describes a novel biochemical mechanism by which glutathione deficiency causes epigenetic impairment of vitamin D metabolism gene in the liver and its contribution to reduced circulating levels of 25(OH)VD 3 in HFD-fed obese mice

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Most of the early studies focused on its effects on the stomach and intestines

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