Plaintiffs assert that side effects such as gallstones and acute gallbladder disease, sometimes resulting in necessary gallbladder removal surgery, were not sufficiently disclosed
Hepatocellular carcinoma (HCC) often develops in the context of obesity-related liver disease, including nonalcoholic steatohepatitis (NASH)
Typical titration schedule in trials: Start at 2 mg weekly Increase every 4 weeks: 2 mg 4 mg 6 mg 9 mg or 12 mg (depending on target dose) This means it takes 3-4 months to reach the maximum dose Meaningful weight loss becomes apparent after reaching therapeutic doses and maintaining them for several weeks
A deficiency in vitamin B12 can cause fatigue, headaches, indigestion, problems with your vision, increased risk of obesity, and cognitive difficulties
It is crucial to keep the capsules in their original packaging, ensuring the container is tightly sealed to maintain its integrity
At the 8 mg dose, reductions were approximately 1.8 percentage points, and the 4 mg dose produced reductions of around 1.1 percentage points