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JAMA 325 (14), 14031413 (2021) J.P.H

Taking too much choline could result in your body smelling fishy, may cause nausea, depression, and could trigger existing epilepsy

Possible serious adverse reactions listed in the prescribing information for these medications include pancreatitis, gallbladder disease, hypoglycemia, kidney problems linked to dehydration, and severe gastrointestinal reactions

Current evidence suggests the class as a whole requires monitoring, though some studies have noted variations between different drugs

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