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The Use of Low-Dose Naltrexone for Chronic Pain Kirbie M Bostick, Andrew G McCarter, Diane Nykamp PMID: 30821677 DOI: 10.4140/TCP.n.2019.43 Review:Med Sci (Basel) 2018 Sep 21;6(4):82

Additionally, cadmium induces oxidative stress in both somatic and germ cells, triggers inflammation, promotes apoptosis in germ cells, and exerts epigenetic modifications (55, 56)

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[5] While copper can potentially cause skin irritation or toxicity, in vitro studies suggest that GHK-Cu complexes may have a lower likelihood of inducing these effects

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