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Proposed Mechanisms (Preclinical) Incretin & Glucose Pathways GLP-1 receptor activation: Investigated for effects on glucose-dependent insulin secretion, gastric emptying, and appetite-related signaling in CNS pathways
Herzmann C et al
Another clinical study showed participants with DPN underwent nerve ultrasonography, neuropathy symptom scoring, and nerve conduction studies before and after one month of GLP-1RA therapy (semaglutide or dulaglutide) [89]
However, keep in mind that it is not necessary to escalate the dose every 4 weeks
A.DkhilM
Gastrointestinal adverse effects of GLP-1 receptor agonists
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