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There's no direct evidence from canine studies, but the rodent findings create a biological rationale for further investigation in larger animal models

On occasion, you may experience some discomfort, bruising, itching, inflammation, or redness at or around the site of injection, and this could last from a few minutes to several days

[Abstract] J Immunother Cancer

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Proc Natl Acad Sci U S A 92:76907694 Zechmann B, Muller M (2010) Subcellular compartmentation of glutathione in dicotyledonous plants