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Hypothalamic Pathway The hypothalamus regulates GHRH and somatostatin secretion, which determine the timing of GH pulses
Moreover, growth hormone actively participates in metabolic activities, enhancing the utilization of fats for energy and sparing glucose
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The latter fact is important as it confirms the potential of IGF-1 DES to improve anabolism even in the setting of poor calorie intake, a function that would make the peptide useful in chronic disease and in individuals who are unable to consume a great deal of calories for a variety of reasons
Jan 2019;68(1):220-225
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